Antibacterials and Antimycotics: Part 1: Synthesis and Activity of 2-Pyrazoline Derivatives.
نویسندگان
چکیده
منابع مشابه
Synthesis and estimations of antimicrobial properties of novel pyrazoline derivatives
Chalcones are the condensation product of acetophenone in combination with aromatic aldehydes in the presence of strong base. Chalcones and their metal complexes having prominent role in modern coordination chemistry. These compounds possessing novel structural features, interesting spectral and magnetic properties, have been the subject of intensive research due to their importance in medical,...
متن کاملSynthesis and Biological Activity of Certain Mannich Bases Derivatives from 1, 2, 4-Triazoles
Substituted 1, 2, 4- Triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. These triazoles were used for preparation of different derivatives by two different schemes. In the first scheme the Mannich bases were prepared from 5- marcapto-s triazole Quinazolines. The 5-Marcato-s-Tr...
متن کاملSynthesis and Antimycobacterial Activity of 2-(Phenylthio) benzoylarylhydrazone Derivatives
A series of new 2-(phenylthio) benzoylaryl hydrazones were synthesized by acid-catalyzed condensation of hydrazide 3 with corresponding aldehydes. The chemical structures of the compounds were elucidated by FT-IR, 1H-NMR and Mass spectra. All newly synthesized compounds were evaluated for their antimycobacterial activities against Mycobacterium tuberculosis H37Rv using the microplate alamar blu...
متن کاملSynthesis and Antimycobacterial Activity of 2-(Phenylthio) benzoylarylhydrazone Derivatives
A series of new 2-(phenylthio) benzoylaryl hydrazones were synthesized by acid-catalyzed condensation of hydrazide 3 with corresponding aldehydes. The chemical structures of the compounds were elucidated by FT-IR, 1H-NMR and Mass spectra. All newly synthesized compounds were evaluated for their antimycobacterial activities against Mycobacterium tuberculosis H37Rv using the microplate alamar blu...
متن کاملSynthesis and Anti-inflammatory Activity of Some 3, 5-Diaryl-2-Pyrazoline Derivatives
Eleven new 3-(4-bromophenyl)-5-(4-fluorophenyl)-2-pyrazoline derivatives 4-9 and 11-15 were synthesized by using 1-(4-bromophenyl)-3-(4-fluorophenyl) prop-2-en-1-one (3). The newly synthesized compounds were evaluated for anti-inflammatory activity against carrageenan edema in albino rats at a dose of 10 mg/kg. All the compounds of this series showed promising anti-inflammatory activity. The mo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1998
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.46.1254